Ravens quarterback Lamar Jackson injured once again and out of the game after only one play against Bills

Lamar Jackson's return to the Baltimore Ravens offense lasted all of one play on Sunday before he was injured once again.

The Baltimore Ravens quarterback started his first game since Oct. 4 against the Buffalo Bills. However, on his first play in nearly a month and the Ravens' first offensive snap of the game, Jackson injured his right thumb.

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Jackson hit his thumb against Greg Rousseau's shoulder and arm as he threw the football. He immediately grabbed the thumb in obvious pain.

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Baltimore Ravens quarterback Lamar Jackson (8) throws against the Buffalo Bills during the first half of an NFL football game in Orchard Park, N.Y., Sunday, Sept. 7, 2025. (AP Photo/Gene J. Puskar)

Jackson was taken to the Ravens' medical tent and then immediately escorted to the team's locker room while wearing a towel around his entire right hand.

The team initially reported Jackson was questionable to return with a right thumb injury, but within a few minutes, it said Jackson was done for the game.

Tyler Huntley took over at quarterback for the Ravens.

And this is all too familiar for Baltimore.

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Tyler Huntley #5 of the Baltimore Ravens looks to pass against the Atlanta Falcons in the second quarter at Mercedes-Benz Stadium on Oct. 11, 2026, in Atlanta, Ga. (Getty Images)

Jackson has played four games for the Ravens this season and has been highly productive, completing 68 of 96 passes for 967 yards, six touchdowns and one interception while adding 144 rushing yards and a touchdown.

The Ravens were 3-1 in his starts before Sunday.

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But Jackson suffered a high-ankle sprain in the Oct. 4 victory over Tennessee and has missed the past three games, with his mobility and ability to tolerate the pain remaining the primary concerns.

This is a breaking story and will be updated as more information becomes available.