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Tuesday, November 10, 2026

CFB top 25 betting lines: LSU favored over Texas, and Indiana over USC

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Week 11 of the college football season is here, with many huge matchups on the slate.

LSU hosts Texas and Georgia plays Missouri in Athens, but that's not all. There are several others that stand out, as Kentucky hosts Florida, Arizona plays Utah in Tucson, and USC heads across the country to face Indiana in Bloomington.

Note: The College Football Playoff rankings drive these matchups, and they will be updated after the new CFP rankings are released on Nov. 10.

All times Eastern. Odds by DraftKings and subject to change.

Illinois at No. 8 UCLA -10
Friday, 9 p.m., Fox

Records: Illinois 6-3, 0-1 vs. AP Top 25; UCLA 9-0, 1-0 vs. AP Top 25

Money line: Illinois (+300); UCLA (-380)
Over/Under: 47.5 (O -112, U -108)

FPI Projection UCLA by 8.8 points with a 74% probability to win game outright

No. 17 Houston -10.5 at Colorado
Friday, 10:15 p.m., ESPN

Records: Houston 7-2, 1-2 vs. AP Top 25; Colorado 3-6, 0-2 vs. AP Top 25

Money line: Houston (-395); Colorado (+310)
Over/Under: 50.5 (O -118, U -102)

FPI Projection Houston by 13.7 points with a 83% probability to win game outright

Duke at No. 1 Miami -13.5
Saturday, Noon, ABC

Records: Duke 7-2, 0-0 vs. AP Top 25; Miami 8-1, 0-1 vs. AP Top 25

Money line: Duke (+410); Miami (-550)
Over/Under: 54.5 (O -105, U -115)

FPI Projection Miami by 17 points with a 88% probability to win game outright

Northwestern at No. 12 Ohio State -12.5
Saturday, Noon, Fox

Records: Northwestern 6-3, 0-2 vs. AP Top 25; Ohio State 6-3, 2-1 vs. AP Top 25

Money line: Northwestern (+360); Ohio State (-470)
Over/Under: 46.5 (O -110, U -110)

FPI Projection Ohio State by 15.1 points with a 85% probability to win game outright

No. 16 Wake Forest -1.5 at SMU
Saturday, Noon, ESPN

Records: Wake Forest 8-1, 1-1 vs. AP Top 25; SMU 7-2, 0-1 vs. AP Top 25

Money line: Wake Forest (-115); SMU (-105)
Over/Under: 61.5 (O -105, U -115)

FPI Projection Wake Forest by 3.2 points with a 59% probability to win game outright

No. 5 Alabama -16.5 at Vanderbilt
Saturday, 12:45 p.m., SEC Network

Records: Alabama 7-2, 2-2 vs. AP Top 25; Vanderbilt 4-5, 0-3 vs. AP Top 25

Money line: Alabama (-850); Vanderbilt (+575)
Over/Under: 50.5 (O -112, U -108)

FPI Projection Alabama by 24.7 points with a 95% probability to win game outright

No. 13 Tennessee -2.5 at Texas A&M
Saturday, 3 p.m., ESPN

Records: Tennessee 7-2, 2-1 vs. AP Top 25; Texas A&M 4-5, 0-4 vs. AP Top 25

Money line: Tennessee (-135); Texas A&M (+114)
Over/Under: 43.5 (O -105, U -115)

FPI Projection Tennessee by 3 points with a 59% probability to win game outright

No. 18 Missouri at No. 2 Georgia -15.5
Saturday, 3:30 p.m., ABC

Records: Missouri 6-3, 1-3 vs. AP Top 25; Georgia 8-1, 3-0 vs. AP Top 25

Money line: Missouri (+500); Georgia (-700)
Over/Under: 47.5 (O -102, U -118)

FPI Projection Georgia by 17.7 points with a 89% probability to win game outright

No. 20 USC at No. 4 Indiana -7.5
Saturday, 3:30 p.m., CBS

Records: USC 7-2, 1-1 vs. AP Top 25; Indiana 8-1, 0-1 vs. AP Top 25

Money line: USC (+230); Indiana (-285)
Over/Under: 49.5 (O -115, U -105)

FPI Projection Indiana by 10.9 points with a 78% probability to win game outright

Baylor at No. 9 BYU -7.5
Saturday, 3:30 p.m., Fox

Records: Baylor 6-3, 0-0 vs. AP Top 25; BYU 7-2, 1-1 vs. AP Top 25

Money line: Baylor (+240); BYU (-298)
Over/Under: 49.5 (O -105, U -115)

FPI Projection BYU by 6.6 points with a 68% probability to win game outright

Boston College at No. 11 Notre Dame -29.5
Saturday, 3:30 p.m., NBC

Records: Boston College 4-5, 0-1 vs. AP Top 25; Notre Dame 8-1, 1-1 vs. AP Top 25

Money line: Boston College (+1800); Notre Dame (-5000)
Over/Under: 52.5 (O -108, U -112)

FPI Projection Notre Dame by 35.4 points with a 98% probability to win game outright

Michigan at No. 23 Oregon -11.5
Saturday, 3:30 p.m., FS1

Records: Michigan 5-4, 1-2 vs. AP Top 25; Oregon 6-3, 3-1 vs. AP Top 25

Money line: Michigan (+340); Oregon (-440)
Over/Under: 38.5 (O -105, U -115)

FPI Projection Oregon by 15.4 points with a 86% probability to win game outright

No. 10 Ole Miss -1.5 at Oklahoma
Saturday, 4:15 p.m., SEC Network

Records: Ole Miss 6-3, 3-3 vs. AP Top 25; Oklahoma 5-4, 2-2 vs. AP Top 25

Money line: Ole Miss (-115); Oklahoma (-105)
Over/Under: 48.5 (O -115, U -105)

FPI Projection Ole Miss by 2.5 points with a 57% probability to win game outright

Oregon State at No. 25 Boise State -13.5
Saturday, 6 p.m., USA Net

Records: Oregon State 5-4, 0-2 vs. AP Top 25; Boise State 8-1, 0-1 vs. AP Top 25

Money line: Oregon State (+390); Boise State (-520)
Over/Under: 65.5 (O -112, U -108)

FPI Projection Boise State by 10.2 points with a 77% probability to win game outright

No. 24 Florida at No. 6 Kentucky -3.5
Saturday, 6:15 p.m., ESPN

Records: Florida 5-4, 2-2 vs. AP Top 25; Kentucky 7-2, 2-2 vs. AP Top 25

Money line: Florida (+140); Kentucky (-166)
Over/Under: 53.5 (O -108, U -112)

FPI Projection Kentucky by 1.3 points with a 54% probability to win game outright

No. 3 Utah -2.5 at No. 22 Arizona
Saturday, 7:30 p.m., Fox

Records: Utah 9-0, 2-0 vs. AP Top 25; Arizona 7-2, 0-2 vs. AP Top 25

Money line: Utah (-142); Arizona (+120)
Over/Under: 54.5 (O -115, U -105)

FPI Projection Utah by 3.6 points with a 60% probability to win game outright

No. 7 Texas at No. 14 LSU -3.5
Saturday, 7:30 p.m., ABC

Records: Texas 7-2, 4-0 vs. AP Top 25; LSU 6-3, 2-2 vs. AP Top 25

Money line: Texas (+150); LSU (-180)
Over/Under: 46.5 (O -108, U -112)

FPI Projection LSU by 0.9 points with a 53% probability to win game outright

Purdue at No. 19 Iowa -16.5
Saturday, 7:30 p.m., NBC

Records: Purdue 3-6, 0-1 vs. AP Top 25; Iowa 7-2, 2-1 vs. AP Top 25

Money line: Purdue (+625); Iowa (-950)
Over/Under: 47.5 (O -112, U -108)

FPI Projection Iowa by 16.2 points with a 87% probability to win game outright

No. 21 South Carolina -7.5 at Arkansas
Saturday, 7:45 p.m., SEC Network

Records: South Carolina 6-3, 2-2 vs. AP Top 25; Arkansas 3-6, 0-4 vs. AP Top 25

Money line: South Carolina (-310); Arkansas (+250)
Over/Under: 51.5 (O -110, U -110)

FPI Projection South Carolina by 10.4 points with a 77% probability to win game outright

No. 15 Texas Tech at Oklahoma State -3.5
Saturday, 9:30 p.m., ESPN

Records: Texas Tech 8-1, 2-0 vs. AP Top 25; Oklahoma State 6-3, 1-1 vs. AP Top 25

Money line: Texas Tech (+142); Oklahoma State (-170)
Over/Under: 72.5 (O -112, U -108)

FPI Projection Oklahoma State by 0.4 points with a 51% probability to win game outright

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