White House trashes 'peanut-sized brain' Jimmy Kimmel after host demands Trump 'resign'

The White House took aim at late-night host Jimmy Kimmel Friday, declaring that his brain has "rotted" after the comedian called on President Donald Trump to "resign."

"Jimmy Kimmel’s case of Trump Derangement Syndrome is so advanced that it has completely rotted his peanut-sized brain," White House spokesperson Davis Ingle told Fox News Digital.

"He’s far more entertaining when you’re laughing at him than with him, but unfortunately, his real talent is his failing ratings," Ingle added. "This statement took more brain cells to write than the average Jimmy Kimmel joke."

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The White House criticized Kimmel after the ABC comedian called on Trump to resign during a post-election monologue, prompting a response from White House spokesman Davis Ingle. (Randy Holmes/Disney via Getty Images; Kevin Dietsch/Getty Images)

The response followed a string of Trump-focused monologues from Kimmel after the midterm elections, with the ABC host celebrating what he described as a Democratic "blue wave" on Tuesday.

During his Wednesday night monologue, Kimmel called on Trump to resign and rejected the president's claim that Republicans would have fared better had he been on the ballot.

"That is such crap," Kimmel said. "You were on the ballot. You’re like dog hair. You’re on everything. You’ve infected every nook and cranny of our lives. You divided this country like no one ever divided it before. The only time you ever brought us together was yesterday, when we all teamed up to get rid of you!"

Kimmel also referred to the president as "Nappy Gilmore" while showing an imagine of Trump appearing to be asleep during a White House meeting, before urging him to "resign."

"Quit already, just quit. Nobody wants you. Even you don’t want to be president anymore. Take that billion dollars’ worth of crypto, buy an island. Maybe Epstein’s island? Wouldn’t that be a perfect end to this story!" Kimmel added.

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Late-night host Jimmy Kimmel speaks onstage during the 2026 Airbnb.org Gala on Oct. 28, 2026, in Los Angeles, Calif. (Stefanie Keenan/Getty Images for Airbnb)

Later in the broadcast, Kimmel addressed a statement Ingle provided to Fox News Digital earlier in the week following the election, in which the spokesman labeled the host a "no-talent loser who has beclowned himself with tanking ratings."

That earlier White House statement had added that Kimmel is "so devoid of actual talent that nobody with any commonsense would ever watch him unless it was to laugh at him."

"Which is kind of the point of the show, but apparently I’ve beclowned myself once again," Kimmel said, acknowledging the statement on his show and referring to Ingle as "Danny Dingle." 

"The last thing I want to do is tell you how to do your job, Danny Dingle, but today seems like a bad day for you to call me a loser," the host added. 

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Late-night host Jimmy Kimmel hosting "Jimmy Kimmel Live!" on Monday, Sept. 28, 2026. (Disney via Getty Images)

Responding to Kimmel’s post-election coverage earlier in the week, media commentator and Hollywood in Toto editor Christian Toto suggested the host's relationship with ABC could face growing financial pressure.

"Jimmy Kimmel long ago traded in comedy for activism. He's a DNC apparatchik, pushing party talking points and occasionally cracking wise along the way. This week's response to the midterms is nothing new," Toto told Fox News Digital Wednesday.

"What is new, though, is the tightrope he's walking with ABC. The network wants sizable budget cuts to keep the show afloat. The two sides will likely come up with a compromise, because, for ABC suits, the show's propaganda purposes overshadow financial concerns. But for how long?" Toto added.

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Fox News Digital’s Hanna Panreck contributed to this report.

Madison Colombo is a writer for Fox News Digital’s Flash, Media, and Culture team, covering daily breaking news and trending topics with an award-winning background in broadcast and digital journalism.