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Monday, September 28, 2026

NFL Week 4: Odds, lines and totals for every game

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One game remains in Week 3, but odds for Week 4 of the NFL season are out.

The Cleveland Browns host the Pittsburgh Steelers on Thursday night to open the action. The Steelers are a 2.5-point favorite in a game with the lowest total of the week (38.5).

The week is full of tight spreads, with 11 games having spreads of four points or less. The Baltimore Ravens (-11.5) hosting the Tennessee Titans and the Miami Dolphins visiting the Minnesota Vikings (-10) are the major outliers on the board.

The Jacksonville Jaguars-Cincinnati Bengals matchup has the highest points total of the week at 51.5. The Detroit Lions-Carolina Panthers tilt on Sunday night is right behind at 50.5.

Week 4 wraps up with an NFC South battle between the New Orleans Saints (-2.5) and Atlanta Falcons on "Monday Night Football" (8:15 p.m. on ESPN).

Here's a look at the odds for every game this week. (You can find our early bets for Week 4 here.)

Note: Odds by DraftKings and subject to change.

Jump to:
PIT-CLE | IND-WSH | NYJ-CHI | NE-BUF
GB-TB | ARI-NYG | DAL-HOU | JAX-CIN
LAR-PHI | TEN-BAL | MIA-MIN | DEN-SF
KC-LV | LAC-SEA | DET-CAR | ATL-NO

Pittsburgh Steelers -2.5 vs. Cleveland Browns
Thursday, 8:15 p.m., Prime Video

Money Line: Steelers (-148); Browns (+124)
Total: 38.5; Opened: 40.5
FPI favorite: Steelers by 1.6 with a 56% probability to win the game outright

Indianapolis Colts -3 vs. Washington Commanders
Sunday, 9:30 a.m., NFL Net

Line movement: Opened Commanders -1.5

Money Line: Colts (-166); Commanders (+140)
Total: 47.5; Opened: 48.5
FPI favorite: Colts by 1 with a 54% probability to win the game outright

New York Jets vs. Chicago Bears -3
Sunday, 1 p.m., FOX

Line movement: Opened Bears -8.5

Money Line: Jets (+130); Bears (-155)
Total: 42.5; Opened: 45.5
FPI favorite: Bears by 4.5 with a 66% probability to win the game outright

New England Patriots vs. Buffalo Bills -7
Sunday, 1 p.m., CBS

Line movement: Opened Bills -3

Money Line: Patriots (+250); Bills (-310)
Total: 48.5; Opened: 49.5
FPI favorite: Bills by 5.7 with a 71% probability to win the game outright

Green Bay Packers -3.5 vs. Tampa Bay Buccaneers
Sunday, 1 p.m., FOX

Line movement: Opened Packers -1.5

Money Line: Packers (-185); Buccaneers (+154)
Total: 39.5; Opened: 47.5
FPI favorite: Buccaneers by 1 with a 54% probability to win the game outright

Arizona Cardinals -1.5 vs. New York Giants
Sunday, 1 p.m., CBS

Line movement: Opened Giants -7

Money Line: Cardinals (-115); Giants (-105)
Total: 44.5; Opened: 45.5
FPI favorite: Cardinals by 1.2 with a 55% probability to win the game outright

Dallas Cowboys vs. Houston Texans -2.5
Sunday, 1 p.m., FOX

Money Line: Cowboys (+114); Texans (-135)
Total: 47.5; Opened: 47.5
FPI favorite: Cowboys by 1.5 with a 56% probability to win the game outright

Jacksonville Jaguars vs. Cincinnati Bengals -2.5
Sunday, 1 p.m., CBS

Money Line: Jaguars (+114); Bengals (-135)
Total: 51.5; Opened: 51.5
FPI favorite: Jaguars by 1.3 with a 55% probability to win the game outright

Los Angeles Rams -1.5 vs. Philadelphia Eagles
Sunday, 1 p.m., FOX

Money Line: Rams (-130); Eagles (+110)
Total: 46.5; Opened: 47.5
FPI favorite: Rams by 1.8 with a 57% probability to win the game outright

Tennessee Titans vs. Baltimore Ravens -11.5
Sunday, 1 p.m., CBS

Line movement: Opened Ravens -8.5

Money Line: Titans (+500); Ravens (-700)
Total: 43.5; Opened: 47.5
FPI favorite: Ravens by 10.1 with a 83% probability to win the game outright

Miami Dolphins vs. Minnesota Vikings -10
Sunday, 4:05 p.m., FOX

Line movement: Opened Vikings -7.5

Money Line: Dolphins (+455); Vikings (-625)
Total: 39.5; Opened: 43.5
FPI favorite: Vikings by 9.8 with a 82% probability to win the game outright

Denver Broncos vs. San Francisco 49ers -3
Sunday, 4:25 p.m., CBS

Money Line: Broncos (+136); 49ers (-162)
Total: 46.5; Opened: 46.5
FPI favorite: 49ers by 7.8 with a 78% probability to win the game outright

Kansas City Chiefs -5.5 vs. Las Vegas Raiders
Sunday, 4:25 p.m., CBS

Money Line: Chiefs (-238); Raiders (+195)
Total: 47.5; Opened: 43.5
FPI favorite: Chiefs by 5.6 with a 70% probability to win the game outright

Los Angeles Chargers vs. Seattle Seahawks -6.5
Sunday, 4:25 p.m., CBS

Line movement: Opened Seahawks -3

Money Line: Chargers (+250); Seahawks (-310)
Total: 43.5; Opened: 45.5
FPI favorite: Seahawks by 6.7 with a 74% probability to win the game outright

Detroit Lions -3.5 vs. Carolina Panthers
Sunday, 8:20 p.m., NBC

Money Line: Lions (-180); Panthers (+150)
Total: 50.5; Opened: 45.5
FPI favorite: Lions by 3.3 with a 62% probability to win the game outright

Atlanta Falcons vs. New Orleans Saints -2.5
Monday, 8:15 p.m., ESPN

Money Line: Falcons (+130); Saints (-155)
Total: 48.5; Opened: 45.5
FPI favorite: Saints by 3.4 with a 63% probability to win the game outright

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