PunchPolice deny misconduct over viral video of suspect arrested in OyoRTP DesportoEstrela da Amadora supera Fazendense com `bis` de Tom MoustierESPNWeek 7 live: Richard TD run puts Indiana ahead of Ohio State in Big Ten showdownESPN DeportesHaaland se viste de héroe para darle el triunfo al City Premier LeagueThe Jerusalem PostEgypt's Sisi seeks parliament's backing to help defend Saudi Arabia if askedZDF heuteAktuelle Pressemitteilungen des ZDFVanguardTinubu scraps recruitment waiver for federal universities, strengthens autonomyColliderThe 6 Best Sci-Fi Books Released Since 2020, RankedSRF News«Wir haben die Schnauze voll» – Schwere Ausschreitungen bei frankreichweiten ProtestenPremium TimesGunmen kill four vigilantes in Plateau communityNOSPolitie houdt verdachte aan na explosie bij kapperszaak in VlaardingenInteriaZełenski traci nadzieję, mówi bez złudzeń. "Ta decyzja to dopiero początek"
The Daily Newsstand · Free, Always
Saturday, October 17, 2026

LSU vs. Mississippi State prediction, odds, time: Week 7 college football picks from proven model

Translate

This page may contain affiliate links. If you click a link and sign up, make a deposit, place a wager, or make a trade, we may earn a commission at no additional cost to you.

SportsLine's model revealed its best bets for Saturday's matchup of the Mississippi State Bulldogs and Lane Kiffin's LSU Tigers

• 2 min read

SEC squads seeking a quick rebound from losses face off in Death Valley, as Lane Kiffin and the No. 22 LSU Tigers host the No. 16 Mississippi State Bulldogs, who list star quarterback Kamario Taylor and running back Fluff Bothwell as doubtful. LSU (4-2, 1-2 SEC) was surprised in a 35-34 OT loss at Kentucky last Saturday, while MSU (4-1, 2-1) was manhandled 56-23 at home by Alabama. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55:

Kickoff is set for noon ET at Tiger Stadium in Baton Rouge, La. The Tigers are 17.5-point favorites, with the over/under at 55.5 in the latest Mississippi State vs. LSU odds. Before making any LSU vs. Mississippi State picks, check out the Mississippi State vs. LSU predictions from the SportsLine Projection Model. 

Mississippi State vs. LSU odds

Mississippi State vs. LSU spread

LSU -17.5

Mississippi State vs. LSU over/under

55.5 points

Mississippi State vs. LSU money line 

LSU -847, Mississippi State +625

Mississippi State vs. LSU picks

See picks at SportsLine

Mississippi State vs. LSU streaming 

Fubo (Try for free)  

 Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after depositing $10:

Top Mississippi State vs. LSU predictions

After simulating Mississippi State vs. LSU 10,000 times, SportsLine model is going Over 55.5 points at betting apps. The Over has been successful 60% of games played involving these teams. LSU's offense ranks among the nation's best, averaging 42 points and 525 yards per game. Leavitt has been productive with 1,495 yards and 10 TDs, but turnover issues (he also has eight INTs) and inconsistent late-game execution have caused issues.

The Bulldogs have shown they can win on the road (Minnesota, South Carolina) and beat ranked teams (Missouri), but their defense was exposed against Alabama. 

SportsLine's model is projecting 63 combined points in this one, making the Over the value 65% of the time. See the model's spread and money-line picks at SportsLine.

How to make Mississippi State vs. LSU picks

In addition to going Over on the total, the model also says one side of the spread hits in nearly 60% of simulations. You can only get the pick at SportsLine. 

So who wins LSU vs. Mississippi State, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that's on a 48-40 run on top-rated CFB picks, and find out.

Why you should trust SportsLine's model

SportsLine's model simulates every FBS game 10,000 times. It enters Week 7 on a 48-40 run on all top-rated college football picks at betting sites, returning more than $400 for $100 players. Anybody following its picks on college football betting sites could have seen strong returns. 

View the original on CBS Sports →

KioskNews shows a cleaned-up reading view extracted from the publisher’s page — the original always lives on their site, not ours.