LSU vs. Mississippi State prediction, odds, time: Week 7 college football picks from proven model
This page may contain affiliate links. If you click a link and sign up, make a deposit, place a wager, or make a trade, we may earn a commission at no additional cost to you.
SportsLine's model revealed its best bets for Saturday's matchup of the Mississippi State Bulldogs and LSU Tigers
• 2 min read
SEC contenders seeking a quick rebound from losses face off in Death Valley, as Sam Leavitt and the No. 22 LSU Tigers host the No. 16 Mississippi State Bulldogs, who may be without star quarterback Kamario Taylor, who is listed as questionable alongside running back Fluff Bothwell. LSU (4-2, 1-2 SEC) was surprised in a 35-34 OT loss at Kentucky last Saturday, while MSU (4-1, 2-1) was manhandled 56-23 at home by Alabama. Another loss for either team here makes it very difficult to climb back into the SEC title race. LSU has won the last three meetings, though this is the first since 2023. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55:
Kickoff is set for noon ET at Tiger Stadium in Baton Rouge, La. The Tigers are 15.5-point favorites, with the over/under at 57.5 in the latest Mississippi State vs. LSU odds. Before making any LSU vs. Mississippi State picks, check out the Mississippi State vs. LSU predictions from the SportsLine Projection Model.
Mississippi State vs. LSU odds
Mississippi State vs. LSU spread | LSU -15.5 |
Mississippi State vs. LSU over/under | 57.5 points |
Mississippi State vs. LSU money line | LSU -667, Mississippi State +500 |
Mississippi State vs. LSU picks | |
Mississippi State vs. LSU streaming | Fubo (Try for free) |
Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after depositing $10:
Top Mississippi State vs. LSU predictions
After simulating Mississippi State vs. LSU 10,000 times, SportsLine model is going Over 57.5 points at betting apps. The Over has been successful 60% of games played involving these teams. LSU's offense ranks among the nation's best, averaging 42 points and 525 yards per game. Leavitt has been productive with 1,495 yards and 10 TDs, but turnover issues (he also has eight INTs) and inconsistent late-game execution have caused issues.
The Bulldogs have been led by Taylor (1,450 yards, 17 TDs), which makes his availability a key variable. He injured his leg in a win over Missouri, then aggravated it against Alabama. The Bulldogs have shown they can win on the road (Minnesota, South Carolina) and beat ranked teams (Missouri), but their defense was exposed against Alabama.
SportsLine's model is projecting 63 combined points in this one, making the Over the value 64% of the time. See the model's spread and money-line picks at SportsLine.
How to make Mississippi State vs. LSU picks
In addition to going Over on the total, the model also says one side of the spread hits in over 50% of simulations. You can only get the pick at SportsLine.
So who wins LSU vs. Mississippi State, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that's on a 48-40 run on top-rated CFB picks, and find out.
Why you should trust SportsLine's model
SportsLine's model simulates every FBS game 10,000 times. It enters Week 7 on a 48-40 run on all top-rated college football picks at betting sites, returning more than $400 for $100 players. Anybody following its picks on college football betting sites could have seen strong returns.
KioskNews shows a cleaned-up reading view extracted from the publisher’s page — the original always lives on their site, not ours.