Deebo Samuel Sr injury update: What happened to 49ers WR vs Seahawks? Latest status

San Francisco 49ers wide receiver Deebo Samuel Sr. appeared to suffer an injury during Sunday’s game against the Seattle Seahawks.

What happened to Deebo Samuel Sr.?

Samuel initially lost possession of the ball on the play, but concern grew when he stayed down on the field before receiving assistance to leave.

49ers insider Jennifer Lee Chan later provided an update, reporting that the wide receiver was moving slowly toward the bench while officials reviewed the play. More concerningly, Samuel appeared to be holding his hamstring.

“Deebo Samuel walking very slowly to the 49ers bench area and play is under review - he is holding his hamstring,” Chan wrote on X.

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Deebo Samuel Sr injury update

The 49ers later confirmed that Samuel had suffered a hamstring injury, ruling the wide receiver out for the remainder of Sunday’s matchup against the Seahawks.

“Injury Update: Deebo Samuel Sr. is out for the remainder of the game (hamstring),” the team announced on X.

How did Samuel get injured?

Samuel was carrying the ball toward the left side of the field when Seahawks linebacker Drake Thomas made the tackle.

Following contact with a Seattle defender, Samuel appeared to fumble as he fell to the ground. He stayed down for several minutes as officials reviewed the play, prompting concern over his condition. The wide receiver eventually stood up, though he appeared to be struggling to walk normally.

The 30-year-old was seen clutching his right thigh while making his way toward the sideline, leading 49ers medical staff to come onto the field and assist him. He ended the game with two catches for 21 yards and two carries for four yards.

49ers injury list grows

Samuel was not the only 49ers receiver to suffer an injury on Sunday. Jacob Cowing also went down with an ankle issue a few plays later while returning a kick.

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Despite entering the matchup with a 4-0 record, San Francisco now faces further challenges as it continues to deal with a depleted offense.

The team was already without three of its top four wide receivers before Sunday's game, with Ricky Pearsall sidelined by a knee injury and De'Zhaun Stribling and Demarcus Robinson both on injured reserve due to ankle injuries.